Fatty liver disease may increase heart failure risk
By Thor Christensen, American Heart Association News
非酒精引起的肝脏脂肪异常堆积可能会大大增加心力衰竭的风险, according to new research.
Nearly 1 in 4 adults in the U.S. 患有非酒精性脂肪性肝病，简称NAFLD. 科学家们已经知道NAFLD会导致永久性肝损伤，并增加动脉粥样硬化的风险, when plaque builds up in the arteries.
但关于NAFLD与心力衰竭关系的研究较少, a term used when the heart isn't pumping as well as it should be. About 6 million U.S. adults have heart failure, which can't be cured but can be treated with lifestyle changes, medications and surgical procedures.
研究人员查看了2005年至2018年的全国健康调查数据，发现超过3个.800万患有NAFLD的成年人，包括大约40万同时患有心力衰竭的人. People with NAFLD who were older, 男性或患有糖尿病或冠心病的人患心力衰竭的风险尤其高. 但即使在调整了年龄、种族和性别之后，研究人员发现，患有NAFLD的成年人的死亡率为3%.发生心力衰竭的可能性是非NAFLD患者的5倍.
"We expected a higher hazard, but not this high," said Dr. Vardhmaan Jain, 他是该研究的首席研究员，也是亚特兰大埃默里大学医学院的心脏病学研究员.
The findings, 在本月的美国心脏协会科学会议上发表, 在完整的结果发表在同行评议的期刊上之前都被认为是初步的吗.
“医生需要密切关注心脏功能和肝脏生物标志物，确保心力衰竭患者不会发展成脂肪肝，反之亦然。," Jain said.
他说，肥胖、糖尿病和高胆固醇通常在NAFLD中起主要作用. He recommended using the AHA's Life's Essential 8 checklist for improving and maintaining cardiovascular health. The list calls for keeping a healthy weight, not smoking, being physically active, eating a healthy diet, getting enough sleep and controlling blood pressure, cholesterol and blood sugar.
“这项研究的结果确实强调了在生命早期重视健康并长期保持沙巴足球体育平台方式的重要性。," Jain said.
他说，这项研究没有证明因果关系，也无法区分不同类型的心力衰竭. 他呼吁对NAFLD患者进行长期跟踪研究，看看哪些因素可能有助于预测心力衰竭.
Dr. P. Barton Duell, who was not involved in the new research, 他说，研究结果“再次提醒人们，NAFLD的诊断与心脏问题的风险增加有关”.
Duell, 奈特心血管研究所和内分泌科的医学教授, Diabetes and Clinical Nutrition at Oregon Health & 波特兰科学大学的主席，最近写了一篇 AHA scientific statement about NAFLD and cardiovascular risk. 他说，NAFLD也与肝硬化的风险增加有关, liver failure and liver cancer. As obesity and metabolic syndrome rates continue to rise, 他敦促医疗专业人员和公众认真对待NAFLD.
“NAFLD是一种未被诊断和低估的健康风险，”Duell说. “这在普通人群中很常见，早期诊断和治疗很重要."
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